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Sildenafil enhances the influence of NO by inhibiting phosphodiesterase type five (PDE5), which is liable for degradation of cGMP during the corpus cavernosum. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum.På den annen facet, mens det er den aktive ingrediensen i Viagra, er Sildenafil tilgjengelig som en generisk ver